China Manufacturer for Raw Material Salicylic Acid - Andrographolide – Chenlv

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China Manufacturer for Raw Material Salicylic Acid - Andrographolide – Chenlv Detail:

CAS No.: 5508-58 -7

Latin name: Andrographis Paniculata (Burm.f) Ness

Part used: whole herb

Appearance: light yellow to white powder

Molecular Formula: C₂₀H₃₀O₅

Molecular Weight:350.455

Test method: HPLC

Specification:

Andrographolide50%

Andrographolide98%

Andrographolide99%

Andrographolide is a labdane diterpenoid that is the main bioactive component of A. paniculata, a well-recognized medicinal plant in Asia. It exerts a wide range of therapeutic actions, including immunosuppressant, antithrombotic, anti-inflammatory, antineoplastic, antiviral, antibacterial, antidiabetic, antioxidative stress, antipyretic, antioedematogenic, and antinociceptive activities.1Andrographolide treatment inhibits nuclear factor kappa B (NF-κB) binding to DNA promoters of target genes (IC50 = ~15 μM), by forming a covalent adduct with reduced cysteine (62) of the NF-κB p50 subunit, and can also induce expression of the CYP1A subfamily of the cytochrome P450 family of enzymes.2,3 At 5 μg/g body weight it can suppress the activation of NF-κB in stimulated endothelial cells, reducing the expression of the cell adhesion molecule E-selectin, abrogating the cytokine- and endotoxin-induced peritoneal infiltration of neutrophils, attenuating septic shock, and preventing allergic lung inflammation in a mouse model of asthma.3

Product packing: 25kg/drum

Validity period: 2 years

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Bear "Customer initially, High quality first" in mind, we do the job closely with our customers and supply them with efficient and skilled providers for China Manufacturer for Raw Material Salicylic Acid - Andrographolide – Chenlv, The product will supply to all over the world, such as: Sao Paulo , Algeria , French , In order to meet more market demands and long-term development, a 150, 000-square-meter new factory is under construction, which will be put into use in 2014. Then, we shall own a large capacity of producing. Of course, we are going to continue improving the service system to meet the requirements of customers, bringing health, happiness and beauty to everyone.

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