China wholesale Pharmaceutical Ingredients - Andrographolide – Chenlv Detail:
CAS No.: 5508-58 -7
Latin name: Andrographis Paniculata (Burm.f) Ness
Part used: whole herb
Appearance: light yellow to white powder
Molecular Formula: C20H30O5
Molecular Weight:350.455
Test method: HPLC
Specification:
Andrographolide50%
Andrographolide98%
Andrographolide99%
Andrographolide is a labdane diterpenoid that is the main bioactive component of A. paniculata, a well-recognized medicinal plant in Asia. It exerts a wide range of therapeutic actions, including immunosuppressant, antithrombotic, anti-inflammatory, antineoplastic, antiviral, antibacterial, antidiabetic, antioxidative stress, antipyretic, antioedematogenic, and antinociceptive activities.1Andrographolide treatment inhibits nuclear factor kappa B (NF-κB) binding to DNA promoters of target genes (IC50 = ~15 μM), by forming a covalent adduct with reduced cysteine (62) of the NF-κB p50 subunit, and can also induce expression of the CYP1A subfamily of the cytochrome P450 family of enzymes.2,3 At 5 μg/g body weight it can suppress the activation of NF-κB in stimulated endothelial cells, reducing the expression of the cell adhesion molecule E-selectin, abrogating the cytokine- and endotoxin-induced peritoneal infiltration of neutrophils, attenuating septic shock, and preventing allergic lung inflammation in a mouse model of asthma.3
Product packing: 25kg/drum
Validity period: 2 years
Product detail pictures:
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With reliable good quality system, great standing and perfect consumer support, the series of products and solutions produced by our organization are exported to quite a few countries and regions for China wholesale Pharmaceutical Ingredients - Andrographolide – Chenlv, The product will supply to all over the world, such as: British , Uganda , Latvia , We hope we can establish long-term cooperation with all of the customers, and hope we can improve competitiveness and achieve the win-win situation together with the customers. We sincerely welcome the customers from all over the world to contact us for anything you need!Welcome all customers both at home and abroad to visit our factory. We hope to have win-win business relationships with you, and create a better tomorrow.
By Mark
from Canada
- 2017.03.07 13:42
The sales manager has a good English level and skilled professional knowledge, we have a good communication. He is a warm and cheerful man, we have a pleasant cooperation and we became very good friends in private.
By Ellen
from San Francisco
- 2017.09.22 11:32