High Quality Nutraceutical Ingredients - Andrographolide – Chenlv Detail:
CAS No.: 5508-58 -7
Latin name: Andrographis Paniculata (Burm.f) Ness
Part used: whole herb
Appearance: light yellow to white powder
Molecular Formula: C20H30O5
Molecular Weight:350.455
Test method: HPLC
Specification:
Andrographolide50%
Andrographolide98%
Andrographolide99%
Andrographolide is a labdane diterpenoid that is the main bioactive component of A. paniculata, a well-recognized medicinal plant in Asia. It exerts a wide range of therapeutic actions, including immunosuppressant, antithrombotic, anti-inflammatory, antineoplastic, antiviral, antibacterial, antidiabetic, antioxidative stress, antipyretic, antioedematogenic, and antinociceptive activities.1Andrographolide treatment inhibits nuclear factor kappa B (NF-κB) binding to DNA promoters of target genes (IC50 = ~15 μM), by forming a covalent adduct with reduced cysteine (62) of the NF-κB p50 subunit, and can also induce expression of the CYP1A subfamily of the cytochrome P450 family of enzymes.2,3 At 5 μg/g body weight it can suppress the activation of NF-κB in stimulated endothelial cells, reducing the expression of the cell adhesion molecule E-selectin, abrogating the cytokine- and endotoxin-induced peritoneal infiltration of neutrophils, attenuating septic shock, and preventing allergic lung inflammation in a mouse model of asthma.3
Product packing: 25kg/drum
Validity period: 2 years
Product detail pictures:
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Persisting in "High quality, Prompt Delivery, Aggressive Price", we have established long-term cooperation with clientele from both equally overseas and domestically and get new and old clients' higher comments for High Quality Nutraceutical Ingredients - Andrographolide – Chenlv, The product will supply to all over the world, such as: Malaysia , United Arab Emirates , Uruguay , For many years, we have adhered to the principle of customer oriented, quality based, excellence pursuing, mutual benefit sharing. We hope, with great sincerity and good will, to have the honor to help with your further market.
By Carlos from Dominica - 2017.07.07 13:00
Reasonable price, good attitude of consultation, finally we achieve a win-win situation,a happy cooperation!
By Olivia from Jakarta - 2017.01.11 17:15