OEM Customized Quercetin Dihydrate Cas 117-39-5 - Andrographolide – Chenlv

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OEM Customized Quercetin Dihydrate Cas 117-39-5 - Andrographolide – Chenlv Detail:

CAS No.: 5508-58 -7

Latin name: Andrographis Paniculata (Burm.f) Ness

Part used: whole herb

Appearance: light yellow to white powder

Molecular Formula: C₂₀H₃₀O₅

Molecular Weight:350.455

Test method: HPLC

Specification:

Andrographolide50%

Andrographolide98%

Andrographolide99%

Andrographolide is a labdane diterpenoid that is the main bioactive component of A. paniculata, a well-recognized medicinal plant in Asia. It exerts a wide range of therapeutic actions, including immunosuppressant, antithrombotic, anti-inflammatory, antineoplastic, antiviral, antibacterial, antidiabetic, antioxidative stress, antipyretic, antioedematogenic, and antinociceptive activities.1Andrographolide treatment inhibits nuclear factor kappa B (NF-κB) binding to DNA promoters of target genes (IC50 = ~15 μM), by forming a covalent adduct with reduced cysteine (62) of the NF-κB p50 subunit, and can also induce expression of the CYP1A subfamily of the cytochrome P450 family of enzymes.2,3 At 5 μg/g body weight it can suppress the activation of NF-κB in stimulated endothelial cells, reducing the expression of the cell adhesion molecule E-selectin, abrogating the cytokine- and endotoxin-induced peritoneal infiltration of neutrophils, attenuating septic shock, and preventing allergic lung inflammation in a mouse model of asthma.3

Product packing: 25kg/drum

Validity period: 2 years

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Our rewards are lower costs,dynamic profits team,specialised QC,potent factories,high-quality services for OEM Customized Quercetin Dihydrate Cas 117-39-5 - Andrographolide – Chenlv, The product will supply to all over the world, such as: Romania , Sweden , Lahore , Now, with the development of internet, and the trend of internationalization, we've got decided to extend business to overseas market. With the propose of bringing more profits to oversea customers by providing directly abroad. So we have changed our mind, from home to abroad, hope to give our customers more profit, and looking forward to more chance to make business.

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